Symptoms we've seen:
- Slow file copying to/from VMs over the network.
- Dropped network connection for entire host that is fixed by reboot.
Some blogs were referring to using registry edits to disable it. However, a faster and easier way in Windows Server 2012 R2 (maybe also Windows Server 2012, but I haven't verified) is by using Windows PowerShell.
To view the VMQ status of your network adapters:
To disable VMQ for all adapters:
Get-NetAdapterVmq | Disable-NetAdapterVmq