I'm doing some work with the release candidate of System Center 2012 - Operations Manager. It requires .NET Framework 4 and I made the mistake of installing .NET Framework 4 before installing IIS on the server. As a result, ASP.NET for .NET Framework 4 is not registered in IIS.
Happily it's an easy fix:
- Open a command prompt
- Change to C:\Windows\Microsoft.NET\Framework64\v4.0.30319
- Run aspnet_regiis.exe -i
After registering you still need to enable it in IIS Manager.
- Open IIS Manager and browse to the server
- Double-click ISAPI and CGI Restrictions
- Allow both ASP.NET v.4 instances
- Run iisreset.exe
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